Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission
Chamma I, Chevy Q, Poncer JC, Levi S
2012 Frontiers in cellular neuroscience 6:5.
A human mutation in Gabrg2 associated with generalized epilepsy alters the membrane dynamics of GABAA receptors
Bouthour W, Leroy F, Emmanuelli C, Carnaud M, Dahan M, Poncer JC, Lévi S. 2012 Cereb Cortex. 22(7):1542-53.
Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice
Khalaf-Nazzal R, Bruel-Jungerman E, Rio JP, Bureau J, Irinopoulou T, Sumia I, Roumegous A, Martin E, Olaso R, Parras C, Cifuentes-Diaz C, Francis F
2013 PLoS One 8:e72622.
Hippocampal development – Old and new findings
Khalaf-Nazzal R, Francis F
2013 Neuroscience 248C:225-242.
Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects
Germain J, Bruel-Jungerman E, Grannec G, Denis C, Lepousez G, Giros B, Francis F, Nosten-Bertrand M.
2013 PLoS One 20;8(9)
New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum
Bahi-Buisson N, Souville I, Fourniol FJ, Toussaint A, Moores CA, Houdusse A, Lemaitre JY, Poirier K, Khalaf-Nazzal R, Hully M, Leger PL, Elie C, Boddaert N, Beldjord C, Chelly J, Francis F
2013 Brain 136:223-244.
Expanding the spectrum of TUBA1A-related cortical dysgenesis to Polymicrogyria
Poirier K, Saillour Y, Fourniol F, Francis F, Souville I, Valence S, Desguerre I, Marie Lepage J, Boddaert N, Line Jacquemont M, Beldjord C, Chelly J, Bahi-Buisson N
2013 Eur J Hum Genet 21:381-385.
Cellular anatomy, physiology and epileptiform activity in the CA3 region of Dcx knockout mice: a neuronal lamination defect and its consequences
Bazelot M, Simonnet J, Dinocourt C, Bruel-Jungerman E, Miles R, Fricker D, Francis F 2012 Eur J Neurosci 35:244-256.
Transient and rapid activation of Akt/GSK-3beta and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens
Salles MJ, Hervé D, Rivet JM, Longueville S, Millan MJ, Girault JA, Mannoury la Cour C.
2013 J Neurochem;125(4):532-44
Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons
Jordi E, Heiman M, Marion-Poll L, Guermonprez P, Cheng SK, Nairn AC, Greengard P, Girault JA (2013). Proc Natl Acad Sci U S A 110:9511-9516.
Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum
Gangarossa G, Espallergues J, Mailly P, De Bundel D, de Kerchove d’Exaerde A, Herve D, Girault JA, Valjent E, Krieger P (2013c). Front Neural Circuits 7:124.
Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens
Gangarossa G, Espallergues J, de Kerchove d’Exaerde A, El Mestikawy S, Gerfen CR, Herve D, Girault JA, Valjent E
(2013a). Front Neural Circuits 7:22.
Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation
Faure C, Ramos M, Girault JA (2013). Cell Mol Life Sci 70:137-152.
Striatal neurones have a specific ability to respond to phasic dopamine release
Castro LR, Brito M, Guiot E, Polito M, Korn CW, Herve D, Girault JA, Paupardin-Tritsch D, Vincent P (2013) . J Physiol 591:3197-3214.
Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1
Bonito-Oliva A, Pallottino S, Bertran-Gonzalez J, Girault JA, Valjent E, Fisone G.
2013 Neuropharmacology.72:197-203
Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia
Girault JA (2012b) . Progress in molecular biology and translational science 106:33-62.
Integrating neurotransmission in striatal medium spiny neurons
Girault JA (2012a). Advances in experimental medicine and biology 970:407-429.
Characterization of dopamine D1 and D2
Gangarossa G, Longueville S, De Bundel D, Perroy J, Herve D, Girault JA, Valjent E (2012). Hippocampus 22:2199-2207.
Focal adhesion kinase splice variants maintain primitive
Despeaux M, Chicanne G, Rouer E, De Toni-Costes F, Bertrand J, Mansat-De Mas V, Vergnolle N, Eaves C, Payrastre B, Girault JA, Racaud-Sultan C (2012) . Stem Cells 30:1597-1610.
Galpha(olf) mutation allows parsing the role of cAMP-dependent
Alcacer C, Santini E, Valjent E, Gaven F, Girault JA, Herve D (2012) . J Neurosci 32:5900-5910.
Postnatal growth defects in mice with constitutive depletion of central serotonin
Narboux-Neme N, Angenard G, Mosienko V, Klempin F, Pitychoutis PM, Deneris E, Bader M, Giros B, Alenina N, Gaspar P.
2013 ACS chemical neuroscience 4:171-181.
Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons
Lokmane L, Proville R, Narboux-Neme N, Gyory I, Keita M, Mailhes C, Lena C, Gaspar P, Grosschedl R, Garel S.
2013 Curr Biol 23:810-816.
A subpopulation of serotonergic neurons that do not express the 5-HT1A autoreceptor
Kiyasova V, Bonnavion P, Scotto-Lomassese S, Fabre V, Sahly I, Tronche F, Deneris E, Gaspar P, Fernandez SP
2013 ACS chemical neuroscience 4:89-95.
Cilia: traffic directors along the road of cortical development.
Métin C, Pedraza M.
2014 Neuroscientist.20(5):468-82.
The birth of the barrels.
Gaspar P, Erzurumlu R.
2013 Developmental cell 27:3-4.
Development of hypothalamic serotoninergic neurons requires Fgf signalling via the ETS-domain transcription factor Etv5b.
Bosco A, Bureau C, Affaticati P, Gaspar P, Bally-Cuif L, Lillesaar C (2013). Development 140:372-384.
Modeling activity and target-dependent developmental cell death of mouse retinal ganglion cells ex vivo.
Voyatzis S, Muzerelle A, Gaspar P, Nicol X (2012). PLoS One 7:e31105.
Insights into the complex influence of 5-HT signaling on thalamocortical axonal system development.
Van Kleef ES, Gaspar P, Bonnin A (2012) Eur J Neurosci 35:1563-1572.
Neurotransmitter release at the thalamocortical synapse instructs barrel formation but not axon patterning in the somatosensory cortex.
Narboux-Neme N, Evrard A, Ferezou I, Erzurumlu RS, Kaeser PS, Laine J, Rossier J, Ropert N, Sudhof TC, Gaspar P (2012). J Neurosci
32:6183-6196.
From glutamatergic dysfunction to cognitive impairment: boundaries in the therapeutic of the schizophrenia
Gaspar PA, Bustamante ML, Rojo LE, Martinez A (2012). Current pharmaceutical biotechnology
13:1543-1548.
Probing the diversity of serotonin neurons
Gaspar P, Lillesaar C.
2012 Philos Trans R Soc Lond B Biol Sci. 5;367(1601):2382-94
Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion
Fernandez SP, Gaspar P.
2012 Neuropharmacology 62:144-154.
Development and critical period plasticity of the barrel cortex
Erzurumlu RS, Gaspar P.
2012 Eur J Neurosci 35:1540-1553.
Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice
Bhansali P, Rayport I, Rebsam A, Mason C. (2014) Neural Dev 9:11.
RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release
Stacey D et al. (2012). RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proc Natl Acad Sci USA 109:21128-21133.
Tangentially Migrating Neurons Assemble a Primary Cilium that Promotes Their Reorientation to the Cortical Plate
Baudoin JP, Viou L, Launay PS, Luccardini C, Espeso Gil S, Kiyasova V, Irinopoulou T, Alvarez C, Rio JP, Boudier T, Lechaire JP, Kessaris N, Spassky N, Métin C.
2012 Neuron. 20;76(6):1108-22
Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin.
Diaz SL, Narboux-Nême N, Trowbridge S, Scotto-Lomassese S, Kleine Borgmann FB, Jessberger S, Giros B, Maroteaux L, Deneris E, Gaspar P.
2013 Eur J Neurosci;38(5):2650-8.
PDE4 control on cAMP/PKA compartmentation revealed by biosensor imaging in neurons
Vincent P, Castro LR, Gervasi N, Guiot E, Brito M, Paupardin-Tritsch D (2012). Hormone and metabolic research 44:786-789.
Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain
Urtikova N, Berson N, Van Steenwinckel J, Doly S, Truchetto J, Maroteaux L, Pohl M, Conrath M
2012. Pain;153(6):1320-31
The orphan receptor GPR3 modulates the early phases of cocaine reinforcement
Tourino C, Valjent E, Ruiz-Medina J, Herve D, Ledent C, Valverde O (2012) . British journal of pharmacology 167:892-904.
Diffusion barriers constrain receptors at synapses
Renner M, Schweizer C, Bannai H, Triller A, Levi S. 2012. PLoS One 7:e43032.
Eye-specific projections of retinogeniculate axons are altered in albino mice
Rebsam A, Bhansali P, Mason CA.
2012 J Neurosci 32:4821-4826.
Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
Danglot L, Freret T, Le Roux N, Narboux Nême N, Burgo A, Hyenne V, Roumier A, Contremoulins V, Dauphin F, Bizot JC, Vodjdani G, Gaspar P, Boulouard M, Poncer JC, Galli T, Simmler MC.
2012 J Neurosci.27;32(26):9007-22.
Receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia
Meffre J, Chaumont-Dubel S, Mannoury la Cour C, Loiseau F, Watson DJ, Dekeyne A, Seveno M, Rivet JM, Gaven F, Deleris P, Herve D, Fone KC, Bockaert J, Millan MJ, Marin P (2012) 5-HT(6). EMBO molecular medicine 4:1043-1056.
Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension.
Launay JM, Herve P, Callebert J, Mallat Z, Collet C, Doly S, Belmer A, Diaz SL, Hatia S, Cote F, Humbert M, Maroteaux L
2012 Blood 16;119(7):1772-80.
p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration
Godin JD, Thomas N, Laguesse S, Malinouskaya L, Close P, Malaise O, Purnelle A, Raineteau O, Campbell K, Fero M, Moonen G, Malgrange B, Chariot A, Metin C, Besson A, Nguyen L.
2012 Developmental cell 23:729-744.
Mutations in GNAL cause primary torsion dystonia
Fuchs T, Saunders-Pullman R, Masuho I, Luciano MS, Raymond D, Factor S, Lang AE, Liang TW, Trosch RM, White S, Ainehsazan E, Herve D, Sharma N, Ehrlich ME, Martemyanov KA, Bressman SB, Ozelius LJ (2012). Nature genetics 45:88-92.
Receptors are required for serotonin-selective antidepressant actions
Diaz SL, Doly S, Narboux-Neme N, Fernandez S, Mazot P, Banas SM, Boutourlinsky K, Moutkine I, Belmer A, Roumier A, Maroteaux L (2012). 5-HT(2B). Mol Psychiatry 17:154-163.
An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning
French CA, Jin X, Campbell TG, Gerfen E, Groszer M, Fisher SE, Costa RM (2012). Mol Psychiatry.17(11):1077-85. doi: 10.1038/mp.2011.105. 2011 Aug 30.
Mitogen- and stress-activated protein kinase 1 is required for specific signaling responses in dopamine-denervated mouse striatum, but is not necessary for l-DOPA-induced dyskinesia
Alcacer C, Charbonnier-Beaupel F, Corvol JC, Girault JA, Hervé D
2014 Neurosci Lett.7;583:76-80
Dampened hippocampal oscillations and enhanced spindle activity in an asymptomatic model of developmental cortical malformations
Cid E, Gomez-Dominguez D, Martin-Lopez D, Gal B, Laurent F, Ibarz JM, Francis F, Menendez de la Prida L.
2014 Front Syst Neurosci.14;8:50.
Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32
Sánchez N, Coura R, Engmann O, Marion-Poll L, Longueville S, Hervé D, Andrés ME, Girault JA.
2014 Neuropharmacology.79:559-66.
Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human
Kielar M, Phan Dinh Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, Oegema R, Mancini GM, Bahi-Buisson N, Olaso R, Le Moing AG, Boutourlinsky K, Boucher D, Carpentier W, Berquin P, Deleuze JF, Belvindrah R, Borrell V, Welker E, Chelly J, Croquelois A, Francis F
2014 Nat Neurosci. 17(7):923-33
Fluorescence-activated sorting of fixed nuclei: a general method for studying nuclei from specific cell populations that preserves post-translational modifications
Marion-Poll L1, Montalban E, Munier A, Hervé D, Girault JA.
2014 Eur J Neurosci.39(7):1234-44.
Analysis of adult neurogenesis:evidence for a prominent « non-neurogenic » DCX-protein pool in rodent brain
Kremer T, Jagasia R, Herrmann A, Matile H, Borroni E, Francis F, Kuhn HG, Czech C
2013 PLoS One 8:e59269.
Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin.
Diaz SL, Narboux-Nême N, Trowbridge S, Scotto-Lomassese S, Kleine Borgmann FB, Jessberger S, Giros B, Maroteaux L, Deneris E, Gaspar P.
2013 Eur J Neurosci.38(5):2650-8
Lack of adenylate cyclase 1 (AC1): consequences on corticospinal tract development and on locomotor recovery after spinal cord injury
Nait Taleb Ali H, Morel MP, Doulazmi M, Scotto-Lomassese S, Gaspar P, Dusart I, Bennis M. Brain Res 1549:1-10. 2014
FAK dimerization controls its kinase-dependent functions at focal adhesions
Brami-Cherrier K1, Gervasi N, Arsenieva D, Walkiewicz K, Boutterin MC, Ortega A, Leonard PG, Seantier B, Gasmi L, Bouceba T, Kadaré G, Girault JA, Arold ST.
2014 EMBO J.18;33(4):356-70
The neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spines.
Gauvain G, Chamma I, Chevy Q, Cabezas C, Irinopoulou T, Bodrug N, Carnaud M, Lévi S, Poncer JC.
2011 Proc Natl Acad Sci U S A. 13;108(37):15474-9
Two novel CLCN2 mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy
Saint-Martin C, Gauvain G, Teodorescu G, Gourfinkel-An I, Fedirko E, Weber YG, Maljevic S, Ernst JP, Garcia-Olivares J, Fahlke C, Nabbout R, LeGuern E, Lerche H, Poncer JC, Depienne C.
2009 Hum Mutat.30(3):397-405
GABA(A) receptor gamma 2 subunit mutations linked to human epileptic syndromes differentially affect phasic and tonic inhibition
Eugène E, Depienne C, Baulac S, Baulac M, Fritschy JM, Le Guern E, Miles R, Poncer JC.
2007 J Neurosci.19;27(51):14108-16.
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses
Scheuber A, Rudge R, Danglot L, Raposo G, Binz T, Poncer JC, Galli T.
2006 Proc Natl Acad Sci U S A. 31;103(44):16562-7.
Hippocampal long term potentiation: silent synapses and beyond
Scheuber A, Miles R, Poncer JC. 2004 J Neurosci.17;24(46):10402-9.
Multiple mechanisms for the potentiation of AMPA receptor-mediated transmission by alpha-Ca2+/calmodulin-dependent protein kinase II
Poncer JC, Esteban JA, Malinow R.
2002 J Neurosci.1;22(11):4406-11
Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics
Poncer JC1, Malinow R.
2001 Nat Neurosci.4(10):989-96
Differential control of GABA release at synapses from distinct interneurons in rat hippocampus
Poncer JC, McKinney RA, Gahwiler BH, Thompson SM.
2000 J Physiol.1;528 Pt 1:123-30.
Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction.
Hayashi Y1, Shi SH, Esteban JA, Piccini A, Poncer JC, Malinow R.
2000 Science.24;287(5461):2262-7.
Mice lacking the serotonin 5-HT2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants.
Diaz SL, Narboux-Nême N, Boutourlinsky K, Doly S, Maroteaux L.
2016 Eur Neuropsychopharmacol;26(2):265-79