Gribaudo S, Robert R, van Sambeek B, Mirdass C, Lyubimova A, Bouhali K, Ferent J, Morin X, van Oudenaarden A, Nedelec S Nat Biotechnol. 2023 Sep 14.
Publications of the Nédélec Team
STEM CELLS IN NEURODEVELOPMENT AND DISEASES
Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification
Mouilleau V, Vaslin C, Robert R, Gribaudo S, Nicolas N, Jarrige M, Terray A, Lesueur L, W Mathis M, Croft G, Daynac M, Rouiller-Fabre V, Wichterle H, Ribes V, Martinat C, Nedelec S Development (2021) 148: dev194514
In vitro models of spinal motor circuit’s development in mammals: achievements and challenges.
Nedelec S, Martinez-Arias A. Curr Opin Neurobiol. (2021) 66: 240-249
Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch.
Kumamoto T, Maurinot F, Barry-Martinet R, Vaslin C, Vandormael-Pournin S, Le M, Lerat M, Niculescu D, Cohen-Tannoudji M, Rebsam A, Loulier K, Nedelec S, Tozer S, Livet J Neuron. 2020 Jun 17;S0896-6273(20)30407-4.
BMP4 patterns Smad activity and generates stereotyped cell fate organization in spinal organoids.
Duval N, Vaslin C, Barata TC, Frarma Y, Contremoulins V, Baudin X, Nedelec S, Ribes VC. Development. 2019 Jul 25;146(14). pii: dev175430.
Serotonin neurons in a dish.
Patricia Gaspar, Stéphane Nedelec Nat Biotechnol. 2016 Jan;34(1):41-2.
Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
Yves Maury, Julien Côme, Rebecca A Piskorowski, Nouzha Salah-Mohellibi, Vivien Chevaleyre, Marc Peschanski, Cécile Martinat, Stéphane Nedelec Nat Biotechnol. 2015 Jan;33(1):89-96.
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.
Esteban O Mazzoni, Shaun Mahony, Michael Closser, Carolyn A Morrison, Stephane Nedelec, Damian J Williams, Disi An, David K Gifford, Hynek Wichterle Nat Neurosci. 2013 Sep;16(9):1219-27.
Genetically-modified human pluripotent stem cells: new hopes for the understanding and the treatment of neurological diseases?
Stéphane Nedelec, Brigitte Onteniente, Marc Peschanski, Cécile Martinat Curr Gene Ther. 2013 Apr;13(2):111-9.
Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues.
Stéphane Nédelec, Mirza Peljto, Peng Shi, Mackenzie W Amoroso, Lance C Kam, Hynek Wichterle J Neurosci. 2012 Jan 25;32(4):1496-506.
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O’Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R Hughes, Peter W Zandstra, Andras Nagy, Jeffrey L Wrana, Benjamin J Blencowe Cell. 2011 Sep 30;147(1):132-46.
Combined microfluidics/protein patterning platform for pharmacological interrogation of axon pathfinding.
Peng Shi, Stephane Nedelec, Hynek Wichterle, Lance C Kam Lab Chip. 2010 Apr 21;10(8):1005-10.
