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Publications of the Nédélec Team

STEM CELLS IN NEURODEVELOPMENT AND DISEASES

Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification

Mouilleau V, Vaslin C, Robert R, Gribaudo S, Nicolas N, Jarrige M, Terray A, Lesueur L, W Mathis M, Croft G, Daynac M, Rouiller-Fabre V, Wichterle H, Ribes V, Martinat C, Nedelec S Development (2021) 148: dev194514

PMID :
33782043

In vitro models of spinal motor circuit’s development in mammals: achievements and challenges.

Nedelec S, Martinez-Arias A. Curr Opin Neurobiol. (2021) 66: 240-249

PMID :
33677159

Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch.

Kumamoto T, Maurinot F, Barry-Martinet R, Vaslin C, Vandormael-Pournin S, Le M, Lerat M, Niculescu D, Cohen-Tannoudji M, Rebsam A, Loulier K, Nedelec S, Tozer S, Livet J Neuron. 2020 Jun 17;S0896-6273(20)30407-4.

PMID :
32559415

BMP4 patterns Smad activity and generates stereotyped cell fate organization in spinal organoids.

Duval N, Vaslin C, Barata TC, Frarma Y, Contremoulins V, Baudin X, Nedelec S, Ribes VC. Development. 2019 Jul 25;146(14). pii: dev175430.

PMID :
31239243

Serotonin neurons in a dish.

Patricia Gaspar, Stéphane Nedelec Nat Biotechnol. 2016 Jan;34(1):41-2.

PMID :
26744978

Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.

Yves Maury, Julien Côme, Rebecca A Piskorowski, Nouzha Salah-Mohellibi, Vivien Chevaleyre, Marc Peschanski, Cécile Martinat, Stéphane Nedelec Nat Biotechnol. 2015 Jan;33(1):89-96.

PMID :
25383599

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.

Esteban O Mazzoni, Shaun Mahony, Michael Closser, Carolyn A Morrison, Stephane Nedelec, Damian J Williams, Disi An, David K Gifford, Hynek Wichterle Nat Neurosci. 2013 Sep;16(9):1219-27.

PMID :
23872598

Genetically-modified human pluripotent stem cells: new hopes for the understanding and the treatment of neurological diseases?

Stéphane Nedelec, Brigitte Onteniente, Marc Peschanski, Cécile Martinat Curr Gene Ther. 2013 Apr;13(2):111-9.

PMID :
23444870

Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues.

Stéphane Nédelec, Mirza Peljto, Peng Shi, Mackenzie W Amoroso, Lance C Kam, Hynek Wichterle J Neurosci. 2012 Jan 25;32(4):1496-506.

PMID :
22279234

An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.

Mathieu Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc, Dave O’Hanlon, Hoon-Ki Sung, Manuel Alvarez, Shaheynoor Talukder, Qun Pan, Esteban O Mazzoni, Stephane Nedelec, Hynek Wichterle, Knut Woltjen, Timothy R Hughes, Peter W Zandstra, Andras Nagy, Jeffrey L Wrana, Benjamin J Blencowe Cell. 2011 Sep 30;147(1):132-46.

PMID :
21924763

Combined microfluidics/protein patterning platform for pharmacological interrogation of axon pathfinding.

Peng Shi, Stephane Nedelec, Hynek Wichterle, Lance C Kam Lab Chip. 2010 Apr 21;10(8):1005-10.

PMID :
20358107

Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord.

Hynek Wichterle, Mirza Peljto, Stephane Nedelec Methods Mol Biol. 2009;482:171-83.

PMID :
19089356

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